基本信息
职称:副研究员
电话:021-31246724
地址:bv伟德国际体育D109室
个人简介
1976年出生,博士,副研究员。
1999-2003山东大学学士、硕士,2005-2009上海交通大学博士学位,2007.9-2008.9,美国密苏里大学丹弗斯植物科学中心访问;2009-2019,中科院植物生理生态所任助理研究员、副研究员,2019年9月起,bv伟德国际体育,副研究员。
主要研究方向(Research Interests)
结合代谢组学与生物化学、细胞生物学、分子遗传学等学科方法,研究细胞器脂质动态平衡及脂质代谢调控植物生理病理的分子机制。承担国家高新计划“生物柴油”项目,先后主持中科院青年基金项目、国家自然科学基金青年和面上项目,参加国家自然科学基金国际合作、重点项目、重大研究计划的研究任务。
获奖情况(Awards)
代表性论文(* corresponding author)
1.Yao H#, Lu Y#, Yang X#, Wang X, Luo Z, Lin D, Wu J* and Xue H*. Arabidopsis Sec14 proteins (SFH5 and SFH7) mediateinterorganelle transport of phosphatidic acid and regulatechloroplast development. Proc. Natl. Acad. Sci. U S A 2023, 120: e2221637120. (research highlights in Nature Plants)
2.Qian W, Zhu Y, Chen Q, Wang S, Chen L, Liu T, Tang H* and YaoH*. Comprehensive metabolomic and lipidomic alterations in response to heat stress during seed germination and seedling growth of Arabidopsis. Front. Plant Sci. 2023, 14.
3.Du X, Yao H, Luo P, Tang X, Xue H*. Cytidinediphosphate diacylglycerol synthase-Mediated phosphatidic acid metabolism is crucial for early embryonic development of Arabidopsis. PLoS Genet. 2022, 18: e1010320.
4.Lin D#, Yao H#, Jia L, Tan J, Xu Z, Zheng W* and Xue H*. Phospholipase D-derived phosphatidic acid promotes root hair development under phosphorus deficiency by suppressing vacuolar degradation of PIN2. New Phytol. 2020, 226: 142–155.
5.Yao H and Xue H*. Phosphatidic acid (PA) plays key roles regulating plant development and stress responses. J. Integr. Plant Biol. 2018, 60:851-863.
6.Wang Y, Yao H* and Xue H*. Lipidomic profiling analysis reveals the dynamics of phospholipid molecules in Arabidopsis thaliana seedling growth. J. Integr. Plant Biol. 2016, 58:890-902. (Cover).
7.Deng T#, Yao Y#, Wang J#, Wang J, Xue H* and Zuo K*. GhLTPG1, a cotton GPI-anchored lipid transfer protein, regulates the transport of phosphatidylinositol monophosphates and cotton fiber elongation. Sci. Rep. 2016, 6:26829.
8.Gao Q#, Lu Y#, Yao H#, Xu Y, Huang W and Wang C*. Phospholipid homeostasis maintains cell polarity, development and virulence in metarhizium robertsii. Environ. Microbiol. 2016, 18:3976-3990.
9.Yu F#, He F#, Yao H, Wang C, Wang J, Li J, Qi X, Xue H*, Ding J* and Zhang P*. Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex. EMBO Rep. 2015, 16:813-823. (recommended by F1000 Prime).
10.Yao H*, Wang G and Wang X. Nuclear translocation of proteins and the effect of phosphatidic acid. Plant Signal. & Behav. 2014, 9:12, e977711.
11.Yao H#, Wang G#, Guo G and Wang X*. Phosphatidic acid interacts with a MYB transcription factor and regulates its nuclear localization and function in Arabidopsis. Plant Cell 2013, 25: 5030-5042. (recommended by F1000 Prime).
12.Yao H and Xue H*. Signals and mechanisms affecting vesicular trafficking during root growth. Curr. Opin. Plant Biol. 2011,14: 571-579.
13.Yao H#, Zhang T#, Xue H, Tang K* and Li R*. Biomimetic affinity purification of Candida antarctica lipase B. J. Chromatogr. B2011, 879: 3896-3900.